General Western Blot Reagents
Abcam AMN082 dihydrochloride, mGlu7 agonist, 50MG
MW 465.5 Da, Purity >98%. Potent, selective, orally active and brain penetrant mGlu7 receptor agonist. Potently inhibits cAMP accumulation and stimulates GTP binding (EC50 = 64-290 nM) in mGluR7 transfected cells. Selective over mGlu1, 2, 3, 4,5, 6, and 8, ionotropic receptors (up to 10 μM). Elevates plasma stress hormones *in vivo*. Induces mGlu7 receptor internalisation in dissociated hippocampal neurones.
The product is subject to the following: Abcam Restricted Use Statement
Abcam KAT13D / CLOCK peptide, 50UG
KAT13D / CLOCK peptide. >95% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: BHLHE8, KIAA0334, CLOCK, Circadian locomoter output cycles protein kaput, hCLOCK, Class E basic helix-loop-helix protein 8, bHLHe8
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clioquinol, Metal chelator and ionophore, 100MG
MW 305.5 Da, Purity >97%. Metal chelator and ionophore with beneficial effects in animal models of neurodegenerative diseases (Alzheimer's, Parkinson's and Huntington's disease). Effects on Alzheimer's disease attributed to copper and zinc chelation or increased level of a metalloprotease. Other actions reported including iron chelation, inhibition of Huntington expression from its mRNA, proteasome inhibition when complexed with copper, and stimulation of tumor necrosis factor-α secretion. Also inhibitor of CLK-1/MCLK1 (an aging-associated protein).
The product is subject to the following: Abcam Restricted Use Statement
Abcam NBQ x , AMPA / kainate antagonist, 50MG
MW 336.28 Da, Purity >99%. Potent, selective and competitive AMPA/kainate receptor antagonist. Neuroprotective and anticonvulsant in vivo. Water-soluble form available - please see NBQX disodium salt (ab120046).
The product is subject to the following: Abcam Restricted Use Statement
Bioworld Blot Stripping Buffer (4X), 250 mL
Product DescriptionBlot stripping buffer (4x) contains enough liquid concentrate to make 1L of 1X solution. It contains 250 mM Tris and 8% SDS. At 25°C, it has a pH value of 6.8.To use this product, dilute it 4 fold with deionized (DI) water and add 0.6% of β-Mercaptoethanol (beta ME). Wash the membrane in this buffer and incubate at 65°C for 30 minutes under constant agitation. Wash the membrane 5X for 5 minutes in PBS-tween20 or TBS-tween20.Product is an irritant hazard.
Abcam BMS 345541, IKK-2 and IKK-1 inhibitor, 10MG
MW 255.32 Da, Purity >98%. Highly selective cell permeable IKK-2 and IKK-1 inhibitor (IC₅₀ values are 0.3 and 4 μM for IKK-2 and IKK-1 respectively). Blocks NF-κB-dependent transcription. Shows anti-inflammatory and radiosensitizing effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Q x -314 bromide (N-Ethyllidocaine bromide), Na+ channel blocker, 100MG
MW 343.3 Da, Purity >99%. A membrane impermeable quaternary lidocaine derivative. Blocks voltage-sensitive Na+ conductance when applied intracellularly. Soluble in 1 ml water to give specified mM/ml concentration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SAG (Smo agonist), Smoothened agonist, 5MG
MW 490.1 Da, Purity >98%. Cell-permeable, selective, potent Smoothened agonist (EC₅₀ = 3 nM). Binds the Smo heptahelical bundle that antagonizes cyclopamine (ab120392) action. Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Do x orubicin hydrochloride, Topoisomerase II inhibitor, 10MG
MW 580 Da, Purity >98%. Topoisomerase II inhibitor (IC₅₀ = 100 nM, Hep3B cells). DNA intercalator that prevents synthesis of nucleic acid. Induces apoptosis.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Anhydrotetracycline hydrochloride, Tetracycline repressor, 500MG
MW 462.9 Da, Purity >98%. Tetracycline repressor and reverse tetracycline repressor effector. Tetracycline (ab141223, ab146579) derivative. Tetracycline-dependent gene expression effector in bacterial expression systems. Binds poorly to the 30S ribosomal subunit. Exhibits no antibiotic activity.
The product is subject to the following: Abcam Restricted Use Statement
Abcam B-Phycoerythrin Conjugation Kit - Lightning-Link, 3 x 60UG
Labeling in < 4 hrs with 30 secs hands-on time using B-Phycoerythrin Conjugation Kit - Lightning-Link ab102871. 100% antibody recovery.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Human IgE protein, 1MG
Human IgE protein is a Human Full Length protein with >90% purity, < 25 EU/mg endotoxin level and suitable for ELISA, ICC and SDS-PAGE. The predicted molecular weight of ab152001 protein is 185 kDa. - Save time and ensure accurate results - use our IgE protein as an isotype control - No cross-reaction from other immunoglobulin isotypes
Protein/ Peptide/ Enzyme Synonyms: Immunoglobulin heavy constant epsilon, Ig epsilon chain C region, Ig epsilon chain C region ND, IGHE
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam HistoReveal (15ml), 15ML
Proteolytic antigen retrieval (PIER) reagent HistoReveal (ab103720).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Recombinant Borrelia burgdorferi VlsE protein, 1MG
Recombinant Borrelia burgdorferi VlsE protein is a Full Length protein, expressed in Escherichia coli, with >95% purity and suitable for SDS-PAGE, WB, ELISA.
Protein/ Peptide/ Enzyme Synonyms: BbuJD1_F36
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam Mitomycin C (MMC), Anticancer and antibiotic agent, 2MG
MW 334.33 Da, Purity >99%. Anticancer and antibiotic agent. Crosslinks DNA. Inhibits DNA synthesis and nuclear division. Also induces apoptosis.
The product is subject to the following: Abcam Restricted Use Statement